Gomez Búxo, Martín D. (2017) PET/MR gatillado para detección de nódulos pulmonares. / PET/ MR trigger for detection of pulmonary nodules. Maestría en Física Médica, Universidad Nacional de Cuyo, Instituto Balseiro.
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Resumen en español
Hace más de dos décadas los equipos híbridos han cobrado importancia en el ambiente médico. La capacidad de brindar información anatómica y funcional los convierte en una herramienta de diagnóstico importante. Un ejemplo de estos equipos es el PET/MR, que por su reciente desarrollo hace que no se tenga una dimensión exacta de su potencial. Para extender el conocimiento sobre el alcance del PET/MR, en el presente trabajo se busca establecer un protocolo para la modalidad PET-MR para la detección de nódulos pulmonares. La región pulmonar presenta dificultades para el estudio por PET y MR. Se buscaran las secuencias de resonancia magnética capaces de sobrepasar los inconvenientes de la región pulmonar. Mientras que en PET, haciendo uso de las opciones más avanzadas que brinda el equipo, se ajusta el algoritmo de reconstrucción para maximizar la detección de lesiones nodulares. Fijado el protocolo para la evaluación pulmonar, se comparan los resultados obtenidos contra la técnica estándar para la evaluación de nódulos en la región pulmonar, el PET-CT. El protocolo de PET-RM elegido, incluye para el estudio de resonancia, las secuencias STIR gatillada y LAVA, la combinación de estas dos secuencias tiene un mayor poder de detección; sin embargo con grandes errores en los valores de representación. En tanto que la adquisición PET en la región pulmonar se realiza en forma gatillada, usando para la reconstrucción TOF y PSF. El algoritmo de reconstrucción se fijó en 3 iteraciones 16 subset y 3mm de filtrado. Por otro lado las diferencias entre los bloques PET de ambos sistemas, fue muy grande presentando mayor detección de nódulos pulmonares el sistema PET/MR.
Resumen en inglés
More than two decades ago, hybrid equipment has gained importance in the medical environment. The ability to provide anatomical and functional information makes them an important diagnostic tool. An example of this equipment is the PET / MR, which due to its recent development does not have an exact dimension of its potential. To extend the knowledge about the scope of the PET / MR, in the present work we seek to establish a protocol for the PET-MR modality for the detection of pulmonary nodules. The pulmonary region presents difficulties for the study by PET and MR. Magnetic resonance sequences capable of overcoming the disadvantages of the lung region will be sought. While in PET, making use of the most advanced options offered by the equipment, the reconstruction algorithm is adjusted to maximize the detection of nodular lesions. The protocol for pulmonary evaluation was established, comparing the results obtained against the standard technique for the evaluation of nodules in the lung region, the PET-CT. The chosen PET-MRI protocol includes, for the resonance study, the triggered STIR and LAVA sequences; the combination of these two sequences has a greater detection power; however with large errors in NP sizes. While PET acquisition in the lung region is performed in a triggered manner, using TOF and PSF reconstruction. The reconstruction algorithm was set to 3 iterations 16 subset and 3mm filtering. On the other hand, the differences between the PET blocks of both systems were very large, with greater detection of pulmonary nodules in the PET / MR system.
| Tipo de objeto: | Tesis (Maestría en Física Médica) |
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| Palabras Clave: | Computerized tomography; Tomografía computerizada; Magnetic resonance; Resonancia magnética; [ Pulmonary nodules; Nódulos pulmonares; Trigger; Gatillado] |
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| Materias: | Medicina > Medicina nuclear |
| Divisiones: | Gerencia de Area Medicina Nuclear |
| Código ID: | 677 |
| Depositado Por: | Tamara Cárcamo |
| Depositado En: | 09 Aug 2018 14:01 |
| Última Modificación: | 09 Aug 2018 14:01 |
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