Corbacho, Ricardo E. (2021) Implementación de SBRT de pulmón evaluando diferentes soluciones tecnológicas / Lung SBRT implementation: an assessment of different techonologicals tools. Maestría en Física Médica, Universidad Nacional de Cuyo, Instituto Balseiro.
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Resumen en español
La SBRT (Stereotactic Body Radiation Therapy) es una modalidad de tratamiento radioterapéutico que resulta ser una síntesis de tecnologías de vanguardia aplicadas a imágenes y a la entrega de dosis muy altas en pocas fracciones (por lo general, no más de 5 [1]). El hecho de que la mayor parte de la dosis entregada en SBRT quede connada en pequeños volúmenes hace que sea elegida en tratamientos de tumores cuya irradiación puede llegar a comprometer órganos periféricos. Un ejemplo de esto es la aplicación de SBRT en tumores pulmonares. En la última década se han elaborado diferentes protocolos tales como el RTOG 0915 y el RTOG 0813, en los que se discuten diferentes aspectos del tratamiento generando un respaldo metodológico que sirve de guía para instituciones que desean implementar la mencionada técnica. Para dicha implementación, sin embargo, es necesario conocer cuáles son las capacidades tecnológicas de cada centro a n de analizar viabilidad y sustentabilidad. En la presente tesis se aborda el análisis de los elementos que mejor se adaptan a SBRT en las distintas etapas del tratamiento, utilizando las herramientas presentes en las instalaciones de la fundación CEMENER, poniendo especial énfasis en las consideraciones propias de esta modalidad (inmovilización de paciente, precisión en ubicación espacial del target, cálculo de dosis, etc). Esto permitiría determinar diferentes soluciones para las demandas terapéuticas que puedan generarse al utilizar SBRT en la institución.
Resumen en inglés
Stereotactic Body Radiation Therapy (SBRT) is a radiotherapy technique in which advanced technologies are applied to images and to high dose delivery in few fractions (no more than 5 [1]. The fact that almost all the dose is left in a well-dened volume, makes SBRT the chosen treatment for tumors whose radiation can affect organs at risk. An example of this is SBRT application to lung tumors. In the last decade, several protocols were elaborated such as RTOG 0915 and 0813 in which many issues about SBRT are discussed, resulting in a guide for many institutions that wish to implement the aforementioned technique. However, for the implementation it is necessary to know what are the technological capabilities of each institution, in order to analyse the viability and sustainability. The present work evaluates different tools available at Centro de Medicina Nuclear y Molecular Entre Ríos, which are used in SBRT treatment, in order to know their effciency, paying special attention to the main aspects of this method (patient inmovilization, accuracy in target position, dose calculation, etc.). As a result, different solutions may be achieved related to solve the possible SBRT therapeutics demands.
| Tipo de objeto: | Tesis (Maestría en Física Médica) |
|---|---|
| Palabras Clave: | Radiotherapy; Radioterapia; Lungs; Pulmones; Cancer; Cáncer; [Estereotactic; Esterotaxia; Stereotactic body radiation therapy; Radioterapia estereotactica de cuerpo; Immobilization; Inmovilización] |
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| Materias: | Medicina > Radioterapia |
| Divisiones: | Centro de Medicina Nuclear y Molecular de Entre Ríos (CEMENER) |
| Código ID: | 953 |
| Depositado Por: | Marisa G. Velazco Aldao |
| Depositado En: | 28 Jul 2021 10:53 |
| Última Modificación: | 28 Jul 2021 12:13 |
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